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Scientific Research Methods

Latest Contributing Articles


Tickling in the Laboratory
Natural tickling cannot be duplicated in the laboratory. As a result, research on tickling has been limited by the experimental methods chosen.
Hypothesis Testing Explained Simply
Hypothesis Testing is used to check whether there is or is not likely to be a difference between one or more data sets. It is the cornerstone of all statistical testing.
Persuasive Research Uses a Triangular Approach
When you get a writing job that needs to be researched it is best to include more than one method of data analysis. This article provides an overview of good practice.
How DNA Sequencing Began
Techniques that allowed for the rapid determination of the order of the nucleotide bases in a molecule of DNA started a new era in scientific research.
Occam's Razor and Scientific Certainty
The simpler the explanation the better. This theory is otherwise know as KISS. It is also the basis of Occam's razor. This is a theory about evidence and method.
How to Measure Osmolarity
Harness the power of water pressure by learning to calculate molecular content.
How to Perform a t-Test in Matlab
Matlab is one of the most popular, powerful statistical software programs available. Running a basic t-test in Matlab helps determine significance between groups.
Statistical Testing in Scientific Research
Statistical tests help establish the reliability and significance of experimental data
How do Scientists Design Valid Experiments?
Modern science was born with the realization that hypotheses must be tested with valid experiments that yield trustworthy data.
Analyzing DNA by Southern Blot
Identifying specific pieces of DNA in a complex mixture is readily accomplished using a method developed by Dr. Edwin Southern, and the technique bears his name.
Are Pets Telepathic?
A California-based experiment seems to show that dogs know when their owners are on their way home.
What Is Western Blotting?
To study the distribution and behavior of proteins in extracts prepared from cells or tissues, methods based on detection using specific antibodies are widely used.
Research Methods in Second Language Acquisition
Researchers examine mistakes made by people who are learning language. What are the learners' errors and what do they reveal about second language acquisition (SLA)?
What Is Gel Electrophoresis?
In much of biological research, samples of DNA, RNA, or protein can be characterized by separating the molecules in a semi-solid medium exposed to an electric current.
Has Kanzi the Bonobo Really Learned Language?
Kanzi is purportedly the first non-human animal to have learned language without explicit training. What comprises his language and how valid are the researchers' claims?
Language Learning in Bonobos and Chimpanzees
Kanzi, a male bonobo, surpassed all other apes not only by learning more language, but by learning it without explicit training, like a human child does.
Male Bonobo Named Kanzi Learned Language
Kanzi is a male bonobo and the first non-human animal to have learned language without explicit training, just like a human child does.
The Rodent AT1R Gene
The regulation of human AGTR1 expression is complex and associated with cardiovascular disease. Animal genes are giving researchers new insight into how this occurs.
Jellyfish Protein GFP in Biomedical Research
Shimomura, Chalfie and Tsien invented a technique that has revolutionised the study of biology.
CERN – The Big Bang Machine
With the much heralded switch on of the Large Hadron Collider, scientists can begin investigating conditions comparable to those at the beginning of time.
Research into the Aging Process
Once thought an impossibly complex problem, the aging process has become the subject of serious scientific research, mainly due to the use of model organisms.
The Polymerase Chain Reaction
Biologists rely on the relatively recent polymerase chain reaction (PCR) technique to study DNA - its sequence, mutations, and structure.
Comparing Two or More Means
Students new to inferential statistics must understand the logic behind the t-test and factorial analysis of variance before memorizing formulas.
Extraneous Variance in Research
One of the ways researchers can control for extraneous variance is by ruling out alternative explanations through good research design.
Understanding Scientific Inquiry
Scientific Inquiry involves higher order critical thinking as students learn to ask questions, design experiments, conduct minds-on investigations, and present findings.